Right abdominal pain is serious if it is sudden, severe, and unrelenting, making it difficult to stand or find comfort. It is often a medical emergency if accompanied by a high fever, persistent vomiting, or a rigid, tender abdomen that hurts to touch. Seek immediate care if you notice yellowing of the skin (jaundice), blood in your stool, or if the pain radiates to your chest or shoulder. In the lower right, specifically, sharp pain that worsens with movement often indicates appendicitis, which requires urgent evaluation to prevent rupture.

